| ORIGINAL ARTICLE |
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| Year : 2020 | Volume
: 3
| Issue : 2 | Page : 93-97 |
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Stereotactic radiosurgery for single or oligometastatic brain lesions: A single institutional experience
Lalit Kashyap, Sayan Paul, P Vijay Anand Reddy, Kausik Bhattacharya, Prashant Upadhyaya, P Vijay Karan Reddy, Madhuri Kavikondala, K Shilpa Reddy
Department of Radiation Oncology, Apollo Hospital, Hyderabad, Telangana, India
Correspondence Address:
Dr. Lalit Kashyap
Department of Radiation Oncology, Apollo Hospital, Hyderabad, Telangana
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/IJNO.IJNO_14_20
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Aim: Intracranial metastases are the most common neurologic complications of systemic cancer. Stereotactic radiosurgery (SRS) is a proven modality for treating single or oligometastatic brain lesions. In this retrospective study, we have analyzed patients data treated in our hospital with SRS.
Materials and Methods: The analysis included 52 patient's data treated between August 2010 and January 2018. These include the patients in the complete remission of the primary disease and have recurred in the brain with one to four metastases after a significant disease-free interval. Patient's case sheets and treatment planning system data were analyzed to collect the data for this study.
Results: Median follow-up was 10 months (range, 1–37 months). There were twenty cases of Ca (cancer) lung, 13 cases of Ca breast, 5 cases of Ca rectum, 4 cases of Ca endometrium, 2 case of Ca esophagus, and 1 case each of alveolar rhabdomyosarcoma of right parotid, Ca ovary, Ca vaginal vault, Ca lacrimal gland, Ca colon, Ca urinary bladder, and Ca prostate. These patients who had a recurrent disease in the brain were treated with doses ranging from 15 to 20 Gy in single fraction, 24 Gy in 3 fractions, 27 Gy in 3 fractions, or 30 Gy in 5 fractions. Median progression-free survival was 9 months, and median overall survival (OS) was 12 months in these patients.
Conclusion: Frameless SRS is an effective treatment of delivering high-dose radiation to patients who develop one to four brain metastasis with comparable median progression free and OS to the previously reported data.
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